منابع مشابه
Treatment of medullary thyroid carcinoma: an update.
Prognosis and treatment effectiveness of medullary thyroid carcinoma (MTC) are largely related to the tumour stage, so that early diagnosis represents an important goal for the management of patients. Recent advances in genetic testing have improved the clinical approach to the familial MTC syndromes. There is general agreement that the primary operation for MTC should obtain the complete remov...
متن کاملMedullary carcinoma of the thyroid: an update
Medullary carcinoma of the thyroid (MTC) represents 5-10% of differentiated thyroid cancers. It derives from the thyroid C-cells which produce calcitonin and are of neuroendocrine origin. It is a rather rare tumour and is accompanied by considerable mortality as it has frequently already metastasised at diagnosis and is not sensitive to either radiation or chemotherapy. Recently it has been sho...
متن کاملThyroid: Medullary Carcinoma
Medullary thyroid cancers (MTC) are rare neuroendocrine tumors arising from the parafollicular C-cells of the thyroid. In this review, we provide a general overview of the classification, pathology, and clinical management of MTC. In the latter half, we survey the underlying genetic framework of MTC and its potential implications within a diagnostic and therapeutic context.
متن کاملPediatric Medullary Thyroid Carcinoma
Medullary thyroid carcinoma (MTC), which originates from thyroid parafollicular C cells, accounts for 3 to 5% of thyroid malignancies. MTC occurs either sporadically or in an inherited autosomal dominant manner. Hereditary MTC occurs as a familial MTC or as a part of multiple endocrine neoplasia (MEN) type 2A and B syndromes. A strong genotype-phenotype correlation has been observed between her...
متن کاملMedullary thyroid carcinoma.
OBJECTIVE This review outlines advances in the diagnosis, genetic testing, and progress in medullary thyroid cancer (MTC) treatment in light of the most recent evidence. METHODS English-language articles pertaining to MTC published up to 2012 were reviewed. The pertinent articles and their references were obtained and those considered relevant were reviewed for inclusion. RESULTS MTC is an ...
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ژورنال
عنوان ژورنال: Journal of Head and Neck Physicians and Surgeons
سال: 2019
ISSN: 2347-8128
DOI: 10.4103/jhnps.jhnps_4_20